Peptide Database

Peptide NameS16

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC139H229N53O33S2

DescriptionStandard

        EMFTILEEYFMYRGRRRRRRRRR
    

Molecular Weight3234.77 Da

Isoelectric Point (pI)11.83

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.66

Charge Density (pH 7.0) 0.2974

GRAVY Index-1.80

Hydrophobic Moment 0.46

Boman Index-0.89

Instability Index230.60

Aliphatic Index 33.91

Aromaticity 0.1739

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1495.11

LogP -12.72

H-bond Donors 60.0

H-bond Acceptors 42.0

Rotatable Bonds 113.0

Heavy Atoms 227.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0004258 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays