Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length365 amino acids

Chemical FormulaC1791H2789N449O545S18

DescriptionStandard

        MQLVIYFLMILTYTHADYPALKTLLSEKGLGGVSQMMSVRIQSELKSTAIPEVRGGIDIKIGTVKYVLSNMHVRQCSMPDPSLVFVQGTGVSVKVSQLSLSITGSWATQFGVIHDHGSFNLAMHNIKIYTLLQLGDDAGRLSITTVSCSADIGGVDIQFHGGASFFFKPFVSSFRKKISDMIREKGEFYSRSSPSEPPFSASVFDVQYAENSMLSLAASEFLVNSAAYAFLRSGVLQINITDDMLSTLYPNMEMQVLLYASETPLFSFSSGVIDVHVPAKFSAVKPDGTLVPLFTLDVDCNFSGSALIDKNLTGAFEMKNPGYSAKYTTYSLMEDNTDKVVHFDLVQVTESSSSVAMESFQESTQ
    

Molecular Weight39908.15 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-9.80

Net Charge (pH 7.4) -10.55

Charge Density (pH 7.0) -0.0268

GRAVY Index0.13

Hydrophobic Moment 0.70

Boman Index0.16

Instability Index36.15

Aliphatic Index 89.15

Aromaticity 0.1014

Extinction Coeff. Reduced 24870.00

Extinction Coeff. Oxidized 24995.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318505 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabarilius grahami [Animal]

FamilyBPI

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence