Peptide Database

Peptide NameHBD-3-1CV

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC216H377N75O59S

DescriptionStandard

        GIINTLQKYYARVRGGRAAVLSALPKEEQIGKASTRGRKCARRKK
    

Molecular Weight5000.84 Da

Isoelectric Point (pI)11.37

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.52

Charge Density (pH 7.0) 0.2388

GRAVY Index-0.78

Hydrophobic Moment 0.64

Boman Index-0.32

Instability Index46.87

Aliphatic Index 78.22

Aromaticity 0.0444

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2249.60

LogP -25.57

H-bond Donors 84.0

H-bond Acceptors 71.0

Rotatable Bonds 177.0

Heavy Atoms 351.0

Ring Count 3.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029449 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEnterococcus faecalis

Activity500 μg/mL

MethodMIC

RECORD: Rec_0158015 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStreptococcus mutans

Activity250 μg/mL

MethodMIC

RECORD: Rec_0240635 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity4000 μg/mL

MethodMIC

RECORD: Rec_0258521 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetActinomyces israelii

Activity7.81 μg/mL

MethodMIC