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MYP_096372
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Basic Information
Palustrin 2CE3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
31 amino acids
C148H243N39O40S3
Standard
Sequence
GLWDSIKNFGKTIALNVMDKIKCKIGGGCPP
Physicochemical Analysis
3304.94 Da
9.24
2.74
2.50
0.0883
0.01
0.69
0.13
22.64
88.06
0.0645
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1265.87
-10.64
44.0
46.0
111.0
230.0
5.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0387230 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0406195 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Palustrin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
12.5 μM
MIC
PaperJ. Zhao et al. / Zoological Science 28 (2011) 112-117. Molecular Cloning of Novel Antimicrobial Peptide Genes from the Skin of the Chinese Brown Frog, Rana chensinensis Evidence URLhttps://www.uniprot.org/uniprotkb/F1AEK7/entry
RECORD: Rec_0413924 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Palustrin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-29
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
64.0 μM
HC50
PaperJ. Zhao et al. / Zoological Science 28 (2011) 112-117. Molecular Cloning of Novel Antimicrobial Peptide Genes from the Skin of the Chinese Brown Frog, Rana chensinensis Evidence URLhttps://www.uniprot.org/uniprotkb/F1AEK7/entry
RECORD: Rec_0418724 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
79015
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial
including resistant Escherichia coli
15 μM
MIC
PaperMolecular cloning of novel antimicrobial peptide genes from the skin of the Chinese brown frog, Rana chensinensis
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