Peptide Database

Peptide NameAntimicrobial peptide Esculentin-2HB1

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC167H275N45O48S2

DescriptionStandard

        GFFSLLSTAAKFLGKTLLKQAGKAGAEAVACKATNQC
    

Molecular Weight3745.37 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1010

GRAVY Index0.33

Hydrophobic Moment 0.58

Boman Index0.17

Instability Index10.68

Aliphatic Index 82.16

Aromaticity 0.0811

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1508.74

LogP -16.95

H-bond Donors 54.0

H-bond Acceptors 54.0

Rotatable Bonds 128.0

Heavy Atoms 262.0

Ring Count 3.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243418 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax hubeiensis [Animal]

FamilyEsculentin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant