Peptide Database

Peptide NameLIB140

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard Statusnot Standard

Sequence Length27 amino acids

Chemical Formula-

Descriptioncontains X representing unresolved or non-standard residue

        MRPEIWAAQELDRFGDEVNAYYARRVX
    

Molecular Weight0.00 Da

Isoelectric Point (pI)0.00

Net Charge (pH 7.0)0.00

GRAVY Index0.00

Boman Index0.00

Instability Index0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0053911 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitystereochemistry not fully resolved due to X residue [Other]

N-TermNone

C-TermNone

Other ModsUnresolved residue X at position 27

Bio-Activity Profile

Function

Mcl-1/Bcl-xL binding BH3-domain mimetic Peptide-protein interaction Protein-binding Apoptosis regulation Anticancer-related

TargetMcl-1 and Bcl-xL anti-apoptotic proteins

MethodFluorescence polarization binding assay