Peptide Database

Peptide NameDefensin-A3 (DefA3) (OaDefA3)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC448H727N133O136S9

DescriptionStandard

        MRTLGLLLALLFLAAQTPAQLMGEEAEEATGRPEATEAQEAAAALMAARAADRHVTDPEQQRIITCSCRTFCFLGERISGRCYQSVFIYRLCCRG
    

Molecular Weight10440.96 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.82

Charge Density (pH 7.0) -0.0152

GRAVY Index0.04

Hydrophobic Moment 0.70

Boman Index0.01

Instability Index36.73

Aliphatic Index 84.53

Aromaticity 0.0632

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4331.63

LogP -45.13

H-bond Donors 159.0

H-bond Acceptors 145.0

Rotatable Bonds 346.0

Heavy Atoms 726.0

Ring Count 10.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0194870 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyAlpha-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic