Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC263H419N69O78S4

DescriptionStandard

        MRYFQMVKQQMNLVEIEAMNSLQELTLEELDNVLGAGGGVIQIHFIQTKQW
    

Molecular Weight5923.82 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-3.40

Net Charge (pH 7.4) -3.68

Charge Density (pH 7.0) -0.0667

GRAVY Index-0.06

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index51.84

Aliphatic Index 103.14

Aromaticity 0.0784

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2412.35

LogP -19.02

H-bond Donors 79.0

H-bond Acceptors 80.0

Rotatable Bonds 206.0

Heavy Atoms 414.0

Ring Count 6.0

Amide Bonds 60.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0234399 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus parasanguinis FW213 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence