Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2318H3628N618O641S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAVLEQELAQLKLPDISGDFRIRHVGKVHYEISRLDLRSFHLPYSRISLVPNVGLQVSISNAFADVDGNWRVKLHFIRDHGSFDLKVENVYIKISLKLGSDASGKPTADTSDCSTRISKVRVHFSGKFGWLYNLFHSAIEPAFRKILETKVCQIVVKSVHDELQPYLRTLPVTARIDARAGIDYSLVAPPTATAQSLDVDLKGEFFSLAHHSAVPFTPLPLAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSMIPKDVEFHLNTTTFSAFIPQLEKMYPDMLMKLRLSAPSAPFLDIGPEGLSLRPVVDIQAYAILPNSSLAPLFLLSLVSNVSAIIDVKSGHIVGSLKVGRMRLSLKHSDVGTFQVRMLQSIMNIFASNILLPRLNARLDEGFPLPLPDRIQLSNILVRFHQNFLLLGADVQYQPR
    

Molecular Weight50730.01 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)3.90

Net Charge (pH 7.4) 2.73

Charge Density (pH 7.0) 0.0085

GRAVY Index0.10

Hydrophobic Moment 0.70

Boman Index0.12

Instability Index30.85

Aliphatic Index 104.12

Aromaticity 0.0965

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076069 VERIFIED: NO

Provenance & Taxonomy

OrganismCiccaba nigrolineata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria