Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC451H725N129O126S7

DescriptionStandard

        MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIPADNPEVVVSLAWDKSLAPKHPGSRKNVACYCRIPACLAGERRYGTCIYQGRLWAFCC
    

Molecular Weight10194.82 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0164

GRAVY Index0.18

Hydrophobic Moment 0.49

Boman Index0.09

Instability Index49.23

Aliphatic Index 99.89

Aromaticity 0.0638

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4041.58

LogP -35.83

H-bond Donors 144.0

H-bond Acceptors 136.0

Rotatable Bonds 324.0

Heavy Atoms 713.0

Ring Count 16.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135112 VERIFIED: NO

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyDefensin

Tax ID9597

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence