Peptide Database

Peptide NameSLAY-screened peptide P1938

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC66H97N15O19S2

DescriptionStandard

        YTSGFCLPIHEMA
    

Molecular Weight1468.70 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.16

Net Charge (pH 7.4) -1.43

Charge Density (pH 7.0) -0.0893

GRAVY Index0.45

Hydrophobic Moment 0.26

Boman Index0.36

Instability Index51.32

Aliphatic Index 67.69

Aromaticity 0.1538

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 530.40

LogP -3.46

H-bond Donors 19.0

H-bond Acceptors 21.0

Rotatable Bonds 43.0

Heavy Atoms 102.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240525 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/