Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC739H1187N187O214S9

DescriptionStandard

        MFPGLLMNLQVYASEVPMFSFQPGVVKLDLAGAVKASAIEPNGTQIPLFKLNVDLQFDGKVWVAAGRLKGSMALQNLTLTLAVSEVGHFETDTLESLVKMGVMAGLAKLNVELGKGIVLPRMRNAQLVNTVLGVEEGFIAMCSDAEVFTDSFN
    

Molecular Weight16404.04 Da

Isoelectric Point (pI)4.91

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.0288

GRAVY Index0.41

Hydrophobic Moment 0.51

Boman Index0.23

Instability Index21.88

Aliphatic Index 106.99

Aromaticity 0.0719

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6358.55

LogP -54.37

H-bond Donors 213.0

H-bond Acceptors 220.0

Rotatable Bonds 548.0

Heavy Atoms 1149.0

Ring Count 19.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352749 VERIFIED: NO

Provenance & Taxonomy

OrganismNotothenia coriiceps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria