Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length306 amino acids

Chemical FormulaC1555H2486N386O441S14

DescriptionStandard

        MLPKQICPEFSKAVQYMEEILSKLPVSLPVDQVSIFEVSLLGPPPITEKSFDLLVKGEFEGRYRHWDLPFPPVKLVLPDVDSRMLLLALSEITANSAGFVHYKAGVLGINITDDMIPKQSPLRLNVKSLTVFVPELPKCFPDSPPLVLQVSARSAPSVSCQPDSLTVQVSAEIQAFAVYPNQTRFPVFQMQADSETAVNVILSEETVGATISIMNFSLTLNFDVVLGKMDSLQKTLNLGLKIMTPFLNERLKNMFPLPTPLVRLQDPIVRVLQGYLIIMTDLQLTPSSHRTMKSEYPPYREPLAVL
    

Molecular Weight34093.60 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-4.23

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.0138

GRAVY Index0.16

Hydrophobic Moment 0.80

Boman Index0.14

Instability Index54.20

Aliphatic Index 106.93

Aromaticity 0.0752

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16055.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169008 VERIFIED: NO

Provenance & Taxonomy

OrganismRanitomeya imitator [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria