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MYP_096060
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Basic Information
Modelin-5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C81H154N22O17
Standard
Sequence
KLAKKLAKLAKLAKAL
Physicochemical Analysis
1708.23 Da
10.70
5.75
5.54
0.3596
0.29
0.78
-0.04
-11.85
153.12
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
655.94
-2.23
23.0
23.0
65.0
120.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0392381 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Modelin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
5.86 μM
PaperBacterial susceptibility and resistance to modelin-5. PMID37869970 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37869970/ PatentUS 2011/0319336 A1
RECORD: Rec_0401081 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
PMID31074477 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31074477/
RECORD: Rec_0410804 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0427209 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
550 μg/mL
LD50
PaperShort bioactive peptides Evidence URLhttps://patents.google.com/patent/US6875744B2/en PatentUS6875744B2
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