Peptide Database

Peptide NamePeptide methionine-tyrosine

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC181H288N50O53S2

DescriptionStandard

        MPPKPDNPSPDASPELSKYMLAVRNYINLITRQRY
    

Molecular Weight4076.66 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0429

GRAVY Index-0.87

Hydrophobic Moment 0.76

Boman Index-0.17

Instability Index75.49

Aliphatic Index 69.71

Aromaticity 0.0857

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1663.59

LogP -15.69

H-bond Donors 55.0

H-bond Acceptors 57.0

Rotatable Bonds 126.0

Heavy Atoms 286.0

Ring Count 9.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214505 VERIFIED: YES

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyPeptide methionine-tyrosine

Tax ID7757

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0368969 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNeuropeptide Y / neuropeptide F

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0386175 VERIFIED: YES

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyFMRFamide related peptide

Tax ID7757

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator