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MYP_096046
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-wrinkle
Wound healing/Regeneration ▸ Wound healing
Standard
6 amino acids
C36H48N6O7
Standard
Sequence
FVAPFP
Physicochemical Analysis
676.80 Da
5.53
-0.24
-0.44
-0.0400
1.40
0.34
0.72
104.63
65.00
0.3333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
191.24
1.00
5.0
7.0
14.0
49.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044921 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0052492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hexapeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Anti-wrinkle Antioxidant Wound healing Autophagy modulation
Women between 25 and 65 years of age to assess the efficacy of the regenerating body complex (RBC) (Randomized clinical trial)
Western blot; Immunofluorescence; Migration assay; Zymography
PaperHexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts PMID25974626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25974626/
RECORD: Rec_0093554 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hexapeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Anti-wrinkle Antioxidant Wound healing Autophagy modulation
3T3-L1 adipocytes (In vitro)
Western blot; Immunofluorescence; Migration assay; Zymography
PaperHexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts PMID25974626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25974626/
RECORD: Rec_0131529 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hexapeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Anti-wrinkle Antioxidant Wound healing Autophagy modulation
Dermal fibroblasts (In vitro)
Western blot; Immunofluorescence; Migration assay; Zymography
PaperHexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts PMID25974626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25974626/
RECORD: Rec_0165949 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hexapeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Anti-wrinkle Antioxidant Wound healing Autophagy modulation
not specified (In vivo)
Western blot; Immunofluorescence; Migration assay; Zymography
PaperHexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts PMID25974626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25974626/
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