Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2325H3698N590O676S17

DescriptionStandard

        AMFLWCVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPVGKVQYSFTGMQIVNLGLPKSALALVPDTGVILSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVTSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQVRNLGCECPLYYTLNVFLAKVDQYAEIEYSMVGSPDISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSLPSQDTDMLYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGGFIPQIEKMYPGLMMKLLVETVKEPLMTFEPNNMTVQASSTVTAYAIQPNSTLSPLFVLNLEASVSTHIYVTELKLAGNLTLNKIDMSLAKSYVGPFQVTSLDNIFTIVLKFAVIPKVNARLQEGYPLPAIGKMQLVNSQLQVLKDYLLIGTDVQFTG
    

Molecular Weight51276.88 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)5.12

Net Charge (pH 7.4) 4.57

Charge Density (pH 7.0) 0.0109

GRAVY Index0.18

Hydrophobic Moment 0.72

Boman Index0.17

Instability Index32.02

Aliphatic Index 103.23

Aromaticity 0.0894

Extinction Coeff. Reduced 44810.00

Extinction Coeff. Oxidized 45060.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294077 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus rhinocerous [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria