Peptide Database

Peptide NameSLAY-screened peptide P117

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H159N29O33S3

DescriptionStandard

        FDNTRMFCTIDIYNTDLHMH
    

Molecular Weight2487.79 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-2.07

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.1037

GRAVY Index-0.35

Hydrophobic Moment 0.28

Boman Index0.01

Instability Index52.12

Aliphatic Index 58.50

Aromaticity 0.1500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1014.48

LogP -8.87

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 79.0

Heavy Atoms 173.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052910 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/