Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC264H424N70O85S7

DescriptionStandard

        MERRMSFMKNSKDILTNVIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
    

Molecular Weight6163.06 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0457

GRAVY Index-0.21

Hydrophobic Moment 0.57

Boman Index-0.01

Instability Index51.31

Aliphatic Index 65.45

Aromaticity 0.0727

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2522.43

LogP -26.07

H-bond Donors 90.0

H-bond Acceptors 90.0

Rotatable Bonds 212.0

Heavy Atoms 426.0

Ring Count 6.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320001 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus pyogenes serotype M6 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence