Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC845H1379N247O246S7

DescriptionStandard

        MKTQRHGPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRALDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQKSPQDCDFKEDGLVKRCVGTVILNQARDSFDISCDKDNRRFARLGNFFRKAKEKIGRGLKKIGQKIKDFWGNLVPRTES
    

Molecular Weight19158.95 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)8.56

Net Charge (pH 7.4) 8.20

Charge Density (pH 7.0) 0.0504

GRAVY Index-0.45

Hydrophobic Moment 0.89

Boman Index-0.12

Instability Index31.92

Aliphatic Index 87.12

Aromaticity 0.0647

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8020.45

LogP -87.36

H-bond Donors 282.0

H-bond Acceptors 263.0

Rotatable Bonds 648.0

Heavy Atoms 1345.0

Ring Count 24.0

Amide Bonds 183.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0006568 VERIFIED: YES

Provenance & Taxonomy

OrganismTrachypithecus cristatus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetBacillus megaterium

RECORD: Rec_0150159 VERIFIED: YES