Peptide Database

Peptide NameDermaseptin-2.2TR

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC133H224N36O40S

DescriptionStandard

        ALWKDILKNVGKAAGKAVLNTVTDMVNE
    

Molecular Weight2999.48 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)0.80

Net Charge (pH 7.4) 0.60

Charge Density (pH 7.0) 0.0286

GRAVY Index0.07

Hydrophobic Moment 0.73

Boman Index0.10

Instability Index6.79

Aliphatic Index 111.43

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1250.52

LogP -11.17

H-bond Donors 42.0

H-bond Acceptors 42.0

Rotatable Bonds 103.0

Heavy Atoms 210.0

Ring Count 2.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0042376 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa trinitatis [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0113975 VERIFIED: NO