Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC206H343N65O59S7

DescriptionStandard

        RTAIHRALICKRMEGHCEAECLTFEVKIGGCRAELTPYCCKRT
    

Molecular Weight4898.78 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.89

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.0671

GRAVY Index-0.21

Hydrophobic Moment 0.33

Boman Index-0.13

Instability Index45.59

Aliphatic Index 70.47

Aromaticity 0.0465

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2009.30

LogP -19.82

H-bond Donors 79.0

H-bond Acceptors 71.0

Rotatable Bonds 165.0

Heavy Atoms 337.0

Ring Count 5.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126949 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus aethiops [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0400226 VERIFIED: NO