Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC360H565N93O91S8

DescriptionStandard

        MTQLLLLFVALLVLVHVPPGRSEFKRCWKGHGACRPYCTKYETYMHLCPDASLCCLPYGLKPLASKPENV
    

Molecular Weight7908.43 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.23

Charge Density (pH 7.0) 0.0529

GRAVY Index0.16

Hydrophobic Moment 0.55

Boman Index0.13

Instability Index57.03

Aliphatic Index 93.29

Aromaticity 0.1000

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2865.00

LogP -18.42

H-bond Donors 104.0

H-bond Acceptors 106.0

Rotatable Bonds 247.0

Heavy Atoms 552.0

Ring Count 18.0

Amide Bonds 71.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0135989 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera musculus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0247746 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera acutorostrata scammoni [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence