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MYP_095775
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Basic Information
CADY-2e (SEQ ID No: 12)
Anticancer
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
27 amino acids
C166H269N51O31
Standard
Sequence
GLWRALWRLLRSLWRLLWSQPKKKRKV
Physicochemical Analysis
3475.24 Da
12.00
8.76
8.55
0.3243
-0.60
0.96
-0.26
91.31
115.56
0.1481
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1371.42
-4.88
53.0
40.0
116.0
248.0
9.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057552 VERIFIED: NO
Provenance & Taxonomy
Synthetic construct [Synthetic]
CADY
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide
HeLa; HS-68 cells
Cellular uptake assay
Evidence URLhttps://patents.google.com/patent/US7943581 PatentUS7943581
RECORD: Rec_0184207 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
CADY
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperCandidate literature: PMID18957965 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957965/
RECORD: Rec_0184287 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
CADY
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PaperSelf-assembled peptide (CADY-1) improved the clinical application of doxorubicin.; Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo. PMID22688249;23000699 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22688249/ PatentUS7943581B2
RECORD: Rec_0349467 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Cysteamide group
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/