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MYP_095771
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Basic Information
Phakellistatin 9
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
LPPYVPPXFV
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0048321 VERIFIED: YES
Provenance & Taxonomy
Phakellia costata [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Allo-Ile
Bio-Activity Profile
Antimicrobial Anticancer
SNU-638
2.2 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0054446 VERIFIED: YES
Provenance & Taxonomy
Phakellia costata [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Allo-Ile
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HCT 116
1 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0083423 VERIFIED: YES
Provenance & Taxonomy
Phakellia costata [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Allo-Ile
Bio-Activity Profile
Antimicrobial Anticancer
SK-HEP-1
12 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0180100 VERIFIED: YES
Provenance & Taxonomy
Phakellia costata [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Allo-Ile
Bio-Activity Profile
Antimicrobial Anticancer
K562
1.1 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0190977 VERIFIED: YES
Provenance & Taxonomy
Phakellia costata [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Allo-Ile
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
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