Peptide Database

Peptide NameApidaecins type 73 [Cleaved into: Apidaecin; Apidaecin-1B (Apidaecin IB); Apidaecin-1A (Apidaecin IA)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length283 amino acids

Chemical FormulaC1446H2290N476O397

DescriptionStandard

        KNFALAILVVTFVVAVFGNTNLDPPTRPTRLRREAKPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAELEAEPGNNRPVYISQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAELEAEPGNNRPVYISQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAKPEAKPGNNRPVYIPQPRPPHPRI
    

Molecular Weight32694.61 Da

Isoelectric Point (pI)10.99

Net Charge (pH 7.0)17.63

Net Charge (pH 7.4) 16.89

Charge Density (pH 7.0) 0.0623

GRAVY Index-1.43

Hydrophobic Moment 0.60

Boman Index-0.36

Instability Index72.40

Aliphatic Index 56.22

Aromaticity 0.0424

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152517 VERIFIED: YES

Provenance & Taxonomy

OrganismApis mellifera [Animal]

FamilyApidaecin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic

TargetGram Negative Bacteria