Peptide Database

Peptide NameHcp1 family type VI secretion system effector

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length570 amino acids

Chemical FormulaC2811H4430N816O838S23

DescriptionStandard

        MTYRPDIHGRGMALSCDKTTTGAWLITSLPVPNYNVCGYGLIRKGDKTTPCPACGKPGMVAEGEARFKVIDIPIAVDGCVVHCGCPEGSNRIIAPLGQWMRAGPSPAEIAQKKQAELIAQRKAEREAEEKRREEERERNRVFAKSCLRGEGCNDAGDQREPHTNFAPMGIYQAVPQTDPVTDTEAPQRAQVVKKKKLIAPEDIPKPKKRSALWKWWNGNYEEMDYQRAVEEAERAQRARAAIAGASVLRPVAGNFAIRGTWAVVGEAATGVAGLPLAAFLIGMMPGRLNDGEQDFIDRMRAEQAREVPTRVRFTWETNSRGNPVPHGWHTPPGQDRVRVRRMEWDDRRKAYTFTTEEDPRITLIWTPDNPGIDVPEHTGNQYPPVLPNPVMVDPLPDDTGLHATTSPAPEERDFADYILILPFPDIPPIYIYLSKPPVEFLEVELYSGFKRRSRQGKYEADHMPSAAAVREYLRQTDPYASKGQLDEMVQDVAAIVIPKEVHQKISETYGGRNTPAQIELDSRNLRAAVERNLDTIKPALKEYGATESQIEAARTKIHKLNSEMGLYKWP
    

Molecular Weight63801.71 Da

Isoelectric Point (pI)6.83

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -1.62

Charge Density (pH 7.0) -0.0010

GRAVY Index-0.63

Hydrophobic Moment 0.77

Boman Index-0.10

Instability Index42.18

Aliphatic Index 71.09

Aromaticity 0.0719

Extinction Coeff. Reduced 87320.00

Extinction Coeff. Oxidized 87820.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017988 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)