Peptide Database

Peptide NameGaegurin-1 (Gaegurin 1; GGN1; Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC155H258N42O41S3

DescriptionStandard

        SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC
    

Molecular Weight3462.16 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)5.42

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.1643

GRAVY Index0.26

Hydrophobic Moment 0.60

Boman Index0.10

Instability Index42.68

Aliphatic Index 89.09

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1360.83

LogP -13.42

H-bond Donors 50.0

H-bond Acceptors 50.0

Rotatable Bonds 121.0

Heavy Atoms 241.0

Ring Count 3.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419105 VERIFIED: YES

Provenance & Taxonomy

OrganismRana rugosa [Animal]

FamilyGaegurin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity50 μg/mL

MethodMIC

RECORD: Rec_0424538 VERIFIED: YES