Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC421H686N118O123S10

DescriptionStandard

        MMKKSFQVSFIVLTIFTILLQVSSGVLGKVRPVRRTCRDFITVQTAKCNDTTCRTDCDQKKAPATAHGFCDPKLNECNCIYSCYKT
    

Molecular Weight9689.32 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)6.51

Net Charge (pH 7.4) 6.10

Charge Density (pH 7.0) 0.0757

GRAVY Index-0.07

Hydrophobic Moment 0.99

Boman Index-0.04

Instability Index35.96

Aliphatic Index 73.60

Aromaticity 0.0814

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3926.13

LogP -42.78

H-bond Donors 146.0

H-bond Acceptors 141.0

Rotatable Bonds 323.0

Heavy Atoms 672.0

Ring Count 11.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364534 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence