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MYP_095743
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Basic Information
IK12-all D (Derived from IK12-all L)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C69H134N24O13
Standard
Sequence
IRVKIRVKIRVK
Physicochemical Analysis
1507.96 Da
12.00
5.76
5.55
0.4798
0.07
0.43
-0.39
-12.18
170.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
647.18
-2.99
25.0
19.0
56.0
106.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0203858 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
15.6 μg/mL
MIC
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0206140 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
31.3 μg/mL
MIC
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0235704 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
62.5 μg/mL
MIC
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0248627 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
7.8 μg/mL
MIC
PMID24211081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24211081/
RECORD: Rec_0282129 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus ATCC 29737
20.769, 83.076 μM
XTT assay; Crystal violet assay
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