Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC256H416N68O83S5

DescriptionStandard

        MNNTNPEIYVQTATDQEIALLVGGAGSGLVKTLTKDCPGFLSNICVNIGFISGCKNC
    

Molecular Weight5934.77 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.82

Charge Density (pH 7.0) -0.0269

GRAVY Index0.25

Hydrophobic Moment 0.51

Boman Index0.20

Instability Index34.03

Aliphatic Index 94.04

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2429.39

LogP -29.24

H-bond Donors 84.0

H-bond Acceptors 87.0

Rotatable Bonds 196.0

Heavy Atoms 412.0

Ring Count 5.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394746 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus sp. DAT741 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria