Peptide Database

Peptide NameEP2C protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC560H895N167O161S6

DescriptionStandard

        RQRLLPFFTSLLLVALLFPGLSQARHVNHSATEALRELREGATGQGTNGSQLLRHPGKRAPIIRRIPYYPEVESDLRIVDCKRSEGFCQEYCNYLETQVGYCSKKKDACCLH
    

Molecular Weight12735.51 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)5.07

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.0452

GRAVY Index-0.41

Hydrophobic Moment 0.66

Boman Index-0.10

Instability Index51.54

Aliphatic Index 85.36

Aromaticity 0.0804

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5308.42

LogP -53.30

H-bond Donors 192.0

H-bond Acceptors 176.0

Rotatable Bonds 422.0

Heavy Atoms 894.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0163368 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli XL-1

Activity50-100 μg/mL

MethodMIC

RECORD: Rec_0412911 VERIFIED: NO