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MYP_095717
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Basic Information
EC-hepcidin2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
87 amino acids
C418H665N115O127S6
Standard
Sequence
MKTFSVAVAVAVVLAFICTQESSALPVTGIEELVEPVSSDNNDNHQGLPVELRERLVNIRKKRAPTDCIPYCYPTGDGFHCGVTCRF
Physicochemical Analysis
9525.84 Da
5.55
-2.36
-2.77
-0.0271
0.05
0.52
0.07
54.55
88.39
0.0690
2980.00
3230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3852.63
-39.65
136.0
133.0
305.0
666.0
14.0
92.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018247 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio vulnificus
PMID21145974 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21145974/
RECORD: Rec_0043991 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
the replication of Singapore grouper iridovirus (SGIV). UPdated 8/2015
PaperMolecular cloning and characterization of two novel hepcidins from orange-spotted grouper, Epinephelus coioides
RECORD: Rec_0057329 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antiviral
(EC-hepcidin1 is more active than EC-hepcidin2)
PaperPubMed PMID: 21145974 PMID21145974 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21145974/
RECORD: Rec_0119095 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antiviral
Singapore grouper iridovirus (SGIV):strongly inhibit the replication of SGIV
PaperPubMed PMID: 21145974 PMID21145974 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21145974/
RECORD: Rec_0288218 VERIFIED: YES
Provenance & Taxonomy
Epinephelus coioides [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 21145974 PMID21145974 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21145974/
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