Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC189H300N48O68S6

DescriptionStandard

        MEELKNTVVTLSDEELKEAAGAAGCGWACTITDDCPNSVFVCC
    

Molecular Weight4525.07 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-6.53

Net Charge (pH 7.4) -6.84

Charge Density (pH 7.0) -0.1519

GRAVY Index0.19

Hydrophobic Moment 0.39

Boman Index0.14

Instability Index36.71

Aliphatic Index 74.88

Aromaticity 0.0465

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1850.52

LogP -21.30

H-bond Donors 67.0

H-bond Acceptors 68.0

Rotatable Bonds 147.0

Heavy Atoms 311.0

Ring Count 4.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294695 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus sp. NSP9.1 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria