Peptide Database

Peptide NameDefb14-1CV

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC221H380N76O56S

DescriptionStandard

        FLPKTLRKFFARIRGGRAAVLNALGKEEQIGRASNSGRKCARKKK
    

Molecular Weight5029.92 Da

Isoelectric Point (pI)11.90

Net Charge (pH 7.0)11.75

Net Charge (pH 7.4) 11.52

Charge Density (pH 7.0) 0.2611

GRAVY Index-0.71

Hydrophobic Moment 0.76

Boman Index-0.32

Instability Index28.83

Aliphatic Index 71.78

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2214.93

LogP -24.04

H-bond Donors 82.0

H-bond Acceptors 69.0

Rotatable Bonds 180.0

Heavy Atoms 354.0

Ring Count 4.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249804 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMonomer: [Pseudomonas aeruginosa PAO1

Activity1.2 μM

MethodMBC

RECORD: Rec_0395372 VERIFIED: YES