Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length474 amino acids

Chemical FormulaC2402H3732N582O688S20

DescriptionStandard

        MQLVIFFLMILTHTYADYPVLKAVLSEKGLRDVSQMMAVWIQNKLKSTEFPEVRGGVDIGIGTVNYAISNIQVVHCSMSGPSIEFEKGTVVSVKVSKLSFAIKGSWKTQFSIIHDGGSFDLAVYNININTLLGLGDEAGRLSITTISCCDDVGGVNIQFHGGASFFFQPFVSTLQGQISEMIRVRICPAIQQAISELKMNLQKMPVSIPVDQYIYLSVLFTSSPAVTDRSFELDIKGEFYSKSFPSEPPFSASAFDIKYAENYMLSLAASEFFVNSAAYAYLSSEVLQINITENMIPKSFPFHLHTSQFGVFIPQLHTLYPNMEMQVLLYASKTPLFSFSSGVIDFQLPAAAKFSVVKPDGTLVPLFRLDVDSSFSGSALIDNKRLTGVFKMKSLTLTVGSSEIGDFKTAMLEQMLVTKVNSFVLPKLNDYLKTGFLLPTLHNFSLINSKLLIENGFVVIFTDVEDSWAVSMKT
    

Molecular Weight52412.11 Da

Isoelectric Point (pI)5.80

Net Charge (pH 7.0)-5.80

Net Charge (pH 7.4) -6.59

Charge Density (pH 7.0) -0.0122

GRAVY Index0.28

Hydrophobic Moment 0.70

Boman Index0.21

Instability Index42.07

Aliphatic Index 98.86

Aromaticity 0.1139

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013190 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria