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MYP_095506
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Basic Information
Peptide 6(lactoferrin 552-563)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H1N1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
12 amino acids
C53H80N16O22
Standard
Sequence
TNGESTADWAKN
Physicochemical Analysis
1293.30 Da
4.37
-1.60
-1.79
-0.1332
-1.48
0.33
-0.20
-25.72
16.67
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
646.70
-9.90
22.0
21.0
41.0
91.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0099386 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
A/Parma/24/09 H1N1:inhibition of virus replication in MDCK cells
0.00005±0.00023 μM
EC50
PMID28878220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28878220/
RECORD: Rec_0123066 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Virus:A/Roma-ISS/02/08 H1N1:inhibition of virus replication in MDCK cells
0.0004±0 μM
EC50
PMID28878220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28878220/
RECORD: Rec_0125183 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
A/Parma/05/06 H3N3
10±120
EC50
PMID28878220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28878220/
RECORD: Rec_0185725 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Lactoferrin-derived peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-H3N2 Replication inhibition
A/Parma0/5/06 H3N2 | MDCK cells
0.00001±0.00012 μM
EC50
Mammalian: 7.2 h; Yeast: >20 h; E. coli: >10 h
PaperLactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors. | Scala MC, Sala M, Pietrantoni A, Spensiero A, Di Micco S, Agamennone M, Bertamino A, Novellino E, Bifulco G, Gomez-Monterrey IM, Superti F, Campiglia P. | Sci Rep. 2017 Sep 6;7(1):10593. | DOI:10.1038/s41598-017-10492-x | PMID:28878220 PMID28878220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28878220/
RECORD: Rec_0197804 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Lactoferrin-derived peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-H1N1 Replication inhibition
A/Roma-ISS/02/08 H1N1 | MDCK cells
0.0004±0.00000002 μM
EC50
Mammalian: 7.2 h; Yeast: >20 h; E. coli: >10 h
PaperLactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors. | Scala MC, Sala M, Pietrantoni A, Spensiero A, Di Micco S, Agamennone M, Bertamino A, Novellino E, Bifulco G, Gomez-Monterrey IM, Superti F, Campiglia P. | Sci Rep. 2017 Sep 6;7(1):10593. | DOI:10.1038/s41598-017-10492-x | PMID:28878220 PMID28878220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28878220/
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