Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC214H325N53O76S5

DescriptionStandard

        MENAKNAFDLDLEVTKSKDVVEPNITSYSFCTPGCGETGSFNSYCC
    

Molecular Weight5016.50 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-4.53

Net Charge (pH 7.4) -4.82

Charge Density (pH 7.0) -0.0985

GRAVY Index-0.33

Hydrophobic Moment 0.36

Boman Index0.03

Instability Index27.96

Aliphatic Index 48.70

Aromaticity 0.1087

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2089.29

LogP -26.38

H-bond Donors 74.0

H-bond Acceptors 77.0

Rotatable Bonds 162.0

Heavy Atoms 348.0

Ring Count 7.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030497 VERIFIED: NO

Provenance & Taxonomy

OrganismAlkalihalobacillus macyae [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria