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MYP_095407
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Basic Information
Esculentin-1V-HN1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
46 amino acids
C212H363N57O59S3
Standard
Sequence
GIFSKFAGKGIKDLIIKGVKGIAKEAGMDVIRTGIDIAGCKIKGEC
Physicochemical Analysis
4750.69 Da
9.39
3.74
3.49
0.0813
0.31
0.68
0.15
-8.77
106.09
0.0435
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1869.84
-15.33
67.0
66.0
172.0
331.0
2.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0233332 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
4.9 μM
MIC
PaperT. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKC6/entry
RECORD: Rec_0280152 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
3.2 μM
MIC
PMID16427248 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16427248/
RECORD: Rec_0341472 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus FDA 209P
4.9 μM
MIC
PMID16427248 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16427248/
RECORD: Rec_0400162 VERIFIED: YES
Provenance & Taxonomy
Odorrana versabilis [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
4.9 μM
MIC
PaperT. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs Evidence URLhttps://www.uniprot.org/uniprotkb/Q1MU19/entry
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