Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC555H890N150O165S4

DescriptionStandard

        PDLNGHEKYGLGNVKYNISRIRVTAVEFPSASISLLPGTGIKLVIANASLTIDMNWSLRTWMFKDTGRSTGYISKVFVTAIFSMPLDHTGHTLISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12432.17 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index0.01

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index12.46

Aliphatic Index 94.91

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5043.90

LogP -53.64

H-bond Donors 182.0

H-bond Acceptors 176.0

Rotatable Bonds 411.0

Heavy Atoms 874.0

Ring Count 18.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024388 VERIFIED: NO

Provenance & Taxonomy

OrganismCrypturellus soui [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria