Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H877N147O163S3

DescriptionStandard

        PDLTGHEKFALGNVKYNISRIHVTAVELPSAYISLLPGSGIKLVIGNASLTIDMSWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNAGPASISLTSCRTTSGDVDIKLNGKT
    

Molecular Weight12204.89 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.11

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index25.95

Aliphatic Index 98.33

Aromaticity 0.0702

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4932.75

LogP -53.18

H-bond Donors 176.0

H-bond Acceptors 172.0

Rotatable Bonds 400.0

Heavy Atoms 859.0

Ring Count 18.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234035 VERIFIED: NO

Provenance & Taxonomy

OrganismCopsychus sechellarum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria