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MYP_095320
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Basic Information
GBVA10-19(Y8E/T15E)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
18 amino acids
C103H170N32O24S
Standard
Sequence
CWVRLGRELLRRLKEPFT
Physicochemical Analysis
2272.72 Da
10.69
2.75
2.53
0.1530
-0.43
0.97
-0.27
77.09
102.78
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
933.47
-5.19
36.0
28.0
75.0
160.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0064246 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
Hepatitis C virus(Jc1-Luc HCVcc) | Huh7.5.1 cells
20 μM
IC50
Mammalian: 1.2 h; Yeast: >20 h; E. coli: >10 h
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. | Liu X, Huang Y, Cheng M, Pan L, Si Y, Li G, Niu Y, Zhao L, Zhao J, Li X, Chen Y, Yang W. | J Virol. 2013 Feb;87(3):1649-57. | DOI:10.1128/JVI.02201-12 | PMID:23175359 PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0213107 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0289047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
hepatitis C virus(Jc1-Luc HCVcc):inhibition of virus entry in Huh7
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0290315 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0396242 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
20 μM
IC50
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/