Peptide Database

Peptide NameDermaseptin-B3 (DRS-B3) (Dermaseptin BIII)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC365H599N95O115S3

DescriptionStandard

        MAFLKKSVFLVLFLGLVSLSICEEEKREEENEEKQEDDEQSEEKRALWKNMLKGIGKLAGQAALGAVKTLVGAE
    

Molecular Weight8254.42 Da

Isoelectric Point (pI)4.91

Net Charge (pH 7.0)-4.47

Net Charge (pH 7.4) -4.74

Charge Density (pH 7.0) -0.0605

GRAVY Index-0.30

Hydrophobic Moment 0.70

Boman Index-0.03

Instability Index58.80

Aliphatic Index 97.57

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3437.49

LogP -28.74

H-bond Donors 117.0

H-bond Acceptors 114.0

Rotatable Bonds 298.0

Heavy Atoms 578.0

Ring Count 5.0

Amide Bonds 78.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0132143 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria