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MYP_095273
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Basic Information
Palustrin-2CG1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
31 amino acids
C147H246N42O40S2
Standard
Sequence
GLWNTIKEAGKKFAINVLDKIRCGIAGGCKT
Physicochemical Analysis
3305.91 Da
9.59
3.74
3.50
0.1206
0.02
0.66
0.07
8.85
94.52
0.0645
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1345.35
-12.32
49.0
46.0
115.0
231.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094712 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-29
Bio-Activity Profile
Antimicrobial Antifungal Toxicity
moderate hemolytic to hRBC
75 μM
HC50
PaperCharacterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis
RECORD: Rec_0124569 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
150 μM
MIC
RECORD: Rec_0219728 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
4.5 μM
MIC
RECORD: Rec_0224472 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Palustrin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID22951323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22951323/
RECORD: Rec_0269369 VERIFIED: YES
Provenance & Taxonomy
Amolops chunganensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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