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MYP_095264
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Basic Information
PL-29
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
15 amino acids
C96H153N21O18
Standard
Sequence
FKKLKKLFSKLFSFK
Physicochemical Analysis
1889.37 Da
10.70
5.75
5.54
0.3836
-0.16
0.77
-0.09
-33.35
78.00
0.2667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
667.30
-0.95
24.0
24.0
69.0
135.0
4.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0405068 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
2 μM
MIC
PMID25169965 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25169965/
RECORD: Rec_0418316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
APD analysis reveals that this sequence is similar (80%) to PL-18 K: 40%, F: 27%, L: 20%, S: 13%. Chemical modification: N-terminal acetylation (XXE) and C-terminal amidation (XXA)
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae ATCC 700603
2 μM
MIC
PaperFunctional synergy of alpha-helical antimicrobial peptides and traditional antibiotics against Gram-negative and Gram-positive bacteria in vitro and in vivo.
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