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MYP_095254
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Basic Information
analog 3 (Derived from Ib-AMP2)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C88H127N33O17
Standard
Sequence
WGRRGWGAGRRYVRW
Physicochemical Analysis
1919.16 Da
12.00
4.76
4.55
0.3173
-1.47
0.77
-0.42
101.95
26.00
0.2667
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
847.82
-6.18
35.0
22.0
58.0
138.0
7.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003861 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (Nala) (CH3-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa(KCTC 1637)
16 μM
MIC
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0018083 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (Nala) (CH3-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0028833 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (Nala) (CH3-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis(KCTC 1917)
8 μM
MIC
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0115079 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (Nala) (CH3-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis(KCTC 3068)
4 μM
MIC
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0192113 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (Nala) (CH3-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus(KCTC 1621)
4 μM
MIC
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
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