Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC542H864N144O148S8

DescriptionStandard

        MRLLLIIAILLFQKLTVTEQLKKCWGEYIRGFCRKICKTTEIREVLCENGRYCCLNIMELEARKKITRPPRPKPVTYAFTFPQEYYEDEQNYTNSNKKFT
    

Molecular Weight12022.05 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)6.45

Net Charge (pH 7.4) 6.11

Charge Density (pH 7.0) 0.0645

GRAVY Index-0.45

Hydrophobic Moment 0.80

Boman Index-0.11

Instability Index37.40

Aliphatic Index 81.90

Aromaticity 0.1200

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4793.25

LogP -36.23

H-bond Donors 173.0

H-bond Acceptors 163.0

Rotatable Bonds 405.0

Heavy Atoms 842.0

Ring Count 18.0

Amide Bonds 108.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290183 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyseter macrocephalus [Animal]

FamilyDefensin

Tax ID9755

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence