Peptide Database

Peptide NameBMP-10

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC550H854N142O153S8

DescriptionStandard

        NAKGNYCKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLEPISILYLDKGVVTYKFKYEGMAVSECGCR
    

Molecular Weight12160.04 Da

Isoelectric Point (pI)8.67

Net Charge (pH 7.0)3.96

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.0366

GRAVY Index-0.21

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index30.56

Aliphatic Index 82.22

Aromaticity 0.1111

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23295.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4700.71

LogP -37.65

H-bond Donors 168.0

H-bond Acceptors 168.0

Rotatable Bonds 393.0

Heavy Atoms 853.0

Ring Count 24.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187391 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsThe active peptide is a homodimer linked by a disulphide bond between cysteine residues at position 72 of each chain. Predicted disulphide bond formation between cysteine residues at positions 7 and 73, 36 and 105, and 40 and 107

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetBone morphogenetic protein receptors (Human)