Peptide Database

Peptide NameSodium channel neurotoxin MeuNaTxalpha-5* (MeuNaTxalpha-5b)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC425H657N115O119S9

DescriptionStandard

        MNYLILISFALLVITGVESARDAYIAKPHNCVYECFDAFSSYCNGVCTKNGAKSGYCQILGTYGNGCWCIALPDNVPIRIPGKCHRR
    

Molecular Weight9570.05 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.14

Charge Density (pH 7.0) 0.0298

GRAVY Index0.19

Hydrophobic Moment 0.67

Boman Index0.15

Instability Index31.28

Aliphatic Index 87.47

Aromaticity 0.1149

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3726.94

LogP -35.16

H-bond Donors 137.0

H-bond Acceptors 133.0

Rotatable Bonds 304.0

Heavy Atoms 668.0

Ring Count 17.0

Amide Bonds 93.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0008563 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilyLong (4 C-C) scorpion toxin; Sodium channel inhibitor; Alpha subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Toxin Non-hemolytic

TargetNo Target Organism Found

RECORD: Rec_0363891 VERIFIED: NO