Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC466H727N125O136S14

DescriptionStandard

        FPDGEFIMQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNAKVENHTECHCSTCYYHKS
    

Molecular Weight10705.42 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)5.92

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.0617

GRAVY Index-0.34

Hydrophobic Moment 0.62

Boman Index-0.02

Instability Index51.63

Aliphatic Index 44.79

Aromaticity 0.1042

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4175.15

LogP -44.49

H-bond Donors 153.0

H-bond Acceptors 159.0

Rotatable Bonds 349.0

Heavy Atoms 741.0

Ring Count 19.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000300 VERIFIED: YES

Provenance & Taxonomy

OrganismOsphranter rufus [Animal]

FamilyGlycoprotein hormones

Tax ID9321

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0200920 VERIFIED: NO

Provenance & Taxonomy

OrganismMonodelphis domestica [Animal]

FamilyGlycoprotein hormones

Tax ID13616

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0219338 VERIFIED: YES

Provenance & Taxonomy

OrganismTrichosurus vulpecula [Animal]

FamilyGlycoprotein hormones

Tax ID9337

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min